HLA-DQ8 : distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DQ8. The world's highest frequencies are observed in Central and South America (up to 80%), then in Siberia (11-22%). It has been suggested that a...
View ArticleHLA-A3: distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-A3, which is divided in two subtypes : A3:01 and A3:02. The former is mostly found in Europe, with lower frequencies across the Middle East, Central...
View ArticleHLA-DR1: distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR1. The maximum frequencies are observed in the Volga-Ural region, among the Mari (24%), Chuvash (18.5%), Kostroma Russians (17.5%) and South Ural...
View ArticleDistribution of HLA-A types by country
I have started a new page listing HLA allele frequencies by country. I have only had time to add HLA-A types so far, but I am planning to add other types too. There are 14 common HLA-A types in Europe....
View ArticleHLA-DR16: distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR16. The maximum frequencies are observed in the United Emirates (18%), Bulgaria (17.5%), Macedonia (15.5%), Greece (13.5%), Albania (12.5%), Serbia...
View ArticleHLA-DR3 : distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR3. The maximum frequencies are observed in Sardinia (56%), the Basque country (19.5%), Ireland (18%), Morocco (16.5%), Tunisia (16.5%), Libya...
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HLA-DR15: distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR15. The maximum frequencies are observed in the Pasiegos of Cantabria in northern Spain (32%), the Chuvash of the Volga region (19.5%), Ireland...
View ArticleHLA-DR7 : distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR7. The maximum frequencies are observed in the Basque country (26 to 31%), northern Catalonia (23%), the Balearic Islands (22%), Cantabria (20%),...
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HLA-DR11 : distribution map, subtypes frequencies and associated medical...
I have made a map showing the allele frequency of HLA-DRB1*11, aka HLA-DR11. It clearly seems to have a West Asian origin, and probably spread alongside Y-DNA haplogroup J2 considering the high...
View ArticleSNPs linked to HLA-DR types in Europeans/Caucasians
The HLA gene regulates our acquired immune system. It is what helps our body identify foreign antigens (bacteria, fungi, viruses) and determine what type of white blood cells and antibodies should be...
View ArticleHLA-DR9 : distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR9. It is overall an North Asian HLA type, although it is also found in Lebanon and the Maghreb (but Lebanese do have 1-2% of North Asian DNA...
View ArticleHLA-DR13 : distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR13. Unlikely most other HLA types, DR13 does not show any specific geographic pattern or associated with ethnic groups or Y-DNA haplogroup. This is...
View ArticleHLA-DR10 : distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR10. The maximum frequencies are observed in the Lebanon (5.2%), Saudi Arabia (4.8%), Palestine (4.7%), Jordan (3.8%), Morocco (3.3%), Algeria (3%),...
View ArticleHLA-DR14 : distribution map, subtypes, SNPs and associated medical conditions
Here is a map showing the allele frequency of HLA-DR14. The maximum frequencies are observed in Kosovo (8.5%), Albania (7.5%), South Italy (7.5%), Georgia (7.5%), Romania (7%), Macedonia (6.7%), Greece...
View ArticleChromosome 6, HLAs, Ethnicity
What causes a huge chunk of chromosome 6 to be inherited from only one parent? I was doing one-to-one comparisons on GEDmatch and noticed that this is the only location where a significant "block" was...
View ArticleFinding a genetically compatible lover - it's now possible !
GenePartner, a Swiss start-up company, now offer a formula to match men and women by analyzing specific genes in their DNA. It has been known for quite some time now that attraction between two...
View ArticleHLA-B27 : distribution map and associated medical conditions
Here is a map showing the allele frequency of HLA-B27. The maximum frequencies are observed among the Saami (20% in northern Sweden, 15% in Norway), then in the rest of Fennoscandia, in Belgium,...
View ArticleDo you know your HLA types ?
The HLA genes play a vital role in our immune system. HLA can confer you immunity against some diseases, but also make you more prone to some autoimmune reactions (check this thread to know more)....
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HLA-DQ2 : distribution map, subtypes, SNPs, and associated medical conditions
Here is a map showing the allele frequency of HLA-DQ2. The world's highest frequencies are observed among the Sardinians (59%), the Basques (48%), the Brahui and Balochi of Pakistan (40%), the...
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HLA-DR4 : distribution map, subtypes frequencies and associated medical...
Here is a map showing the allele frequency of HLA-DR4. The maximum frequencies are observed among Murmansk Saami, Norwegians, Welsh, Southwest English, Belgians and Armenians. Subtypes DR4 has over 100...
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